Normalized Resistance Interpretation as a Tool for Establishing Epidemiological MIC Susceptibility Breakpoints

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منابع مشابه

Establishing MIC breakpoints and the interpretation of in vitro susceptibility tests.

The purpose of undertaking susceptibility testing, by whatever method, is to attempt to integrate the susceptibility of a population of potential pathogens with the pharmacokinetics of the antimicrobial and, whenever possible, to review this relationship in the light of clinical experience following therapy in clinical trials. Breakpoints are discriminatory antimicrobial concentrations used in ...

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European harmonization of MIC breakpoints for antimicrobial susceptibility testing of bacteria.

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A new method for normalized interpretation of antimicrobial resistance from disk test results for comparative purposes.

OBJECTIVE To evaluate a calibration method for disk diffusion antibiotic susceptibility tests, using zone diameter values generated in the individual laboratory as the internal calibrator for combinations of antibiotic and bacterial species. METHODS The high-zone side of zone histogram distributions was first analyzed by moving averages to determine the peak position of the susceptible popula...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2010

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.01101-10